Active Ingredient: Tilmicosin
Description: light yellow to brown red clear liquid
Pharmacodynamics: Tilmicosin is one type of semi-synthetic macrolide antibiotics with similar mechanism as tylosin and is very effective against Mycoplasma. Gram-positive bacteria which are sensitive to tilmicosin are Staphylococcus (including MRSA), Streptococcus spp., Bacillus anthracis, Erysipeloidrix insidiosia, Listeria monocytogenes, Clostridium putrefaciens, Clostridium chauvoei. Gram-negative bacteria which are sensitive to tilmicosin are Haemophilus, Neisseria meningitides, Pasteurella. The effect of tilmicosin on Actinobacillus pleuropneumoniae, Pasteurella, Mycoplasma is better than tylosine. Pasteurella hemolytica is also sensitive to tilmicosin.
Pharmacokinetics: oral dosage reacts and penetrates quickly with over 2L/kg. The concentration inside the lung is high with a half-life decay time of one to two days making its effective time longer.
1. Not suggested to administrate with other macrolides and lincosamides due to same mechanism
2. Administrate with β-lactam antibiotics will cause antagonism to the drug.
Indication: Macrolide antibiotics. In treatment for respiratory infections caused by Pasteurella and Mycoplasma.
Administration and Dosage: oral use, 0.75ml/L for 3 days
Contraindications: the toxicity is mainly on the circulatory system which may cause tachycardia and decreased contractility
Precaution: do not use on layers during laying.
Withdrawal Time: Poultry: 12 days
Storage: protect it from light, store in a tightly sealed container