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Doxycycline Hyclate Soluble PowderVeterinary drug name Generic Name:Doxycycline Hyclate Soluble Powder Trade Name: Chinese name: 盐酸多西环素可溶性粉 Active Ingredient: Doxycycline Hyclate Description: Light yellow or yellow crystalize powder Pharmacodynamics: Tetracycline antibiotics. Doxycycline can bind to 30s ribosomal subunit to interfere the tRNA-mRNA complex formation and abort protein synthesis to inhibit bacterial growth. Doxycycline is effective against many gram positive and negative bacteria. Bacteria has cross tolerance between doxycycline and oxytetracycline. Pharmacokinetics: Doxycycline has quick internal absorption which is less affected by food with high utilization and penetration. It has a great dispersity an effective concentration for a long period of time. The protein binding rate in porcine is 93%. Indications: use in treatment for porcine and poultry respiratory infections caused by Gram positive and negative bacteria such as E. coli, Salmonella, Pasteurella, and Mycoplasma. Administration and Dosage: oral dosage, porcine: 25~50mg/L; poultry: 300mg/L for 3~5 days. Contraindications: long term usage can cause double infection and damage liver. Precaution: avoid taking doxycycline with high calcium content feed. Withdrawal Time: 28 days. Do not use on layers during laying. Storage: protect it from light, store in a tightly sealed container in a dry place. |